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1d 1d 39 1d 39 160All CAMB Faculty | CB Faculty | CPM Faculty | DSRB Faculty | G&E Faculty | GTV Faculty | MVP Faculty
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Michael C. Abt, PhD
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Stella T Chou, M.D.
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Michael A. Pack, MD
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Kimberly L Gallagher
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Alex J Hughes
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Hongjun Song, Ph.D.
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Olena Jacenko
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Wei Tong, PhD
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Kang I Ko
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Shuying Yang
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Faculty areas of research in DSRB can be broken up into the following eight categories:
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| Faculty | 33Brief Research Description | 8
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| Marisa Bartolomei | 71The research in my laboratory focuses on the study of genomic imprinting and X inactivation in mice. | 8
| Colin Conine | 54The functions of small RNAs in fertility, inheritance, and development. | 8
| Stephen DiNardo | 47Stem Cells, Niche, Epithelial Morphogenesis, Cell Polarity | 8
| Christopher Lengner | 16fInterested in the mechanisms by which both somatic and embryonic stem cells acquire and maintain developmental potency. We are also exploring how deregulation of these mechanisms can contribute to oncogenic transformation and tumorigenesis, and how we can learn to manipulate these mechanisms for application in disease modeling and regenerative medicine | 8
| Mary Mullins | 75BMP signal transduction; molecular mechanisms of cell specification and maternal control in vertebrates. | 8
| P. Jeremy Wang | b1Regulation of meiosis, piRNA biogenesis, DNA recombination, chromosome segregation, DNA double-strand break repair, chromosome synapsis, male infertility in humans. | 8
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| Faculty | 33Brief Research Description | 8
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| Montserrat C Anguera | 71Roles of long noncoding RNAs during early development and how their misregulation results in disease | 8
| Elizabeth Bhoj | baOur lab works in translational genetics to improve diagnosis and treatment through the discovery, mechanistic understanding, and targeted treatment of novel human syndromes. | 8
| Colin Conine | 54The functions of small RNAs in fertility, inheritance, and development. | 8
| E. Bryan Crenshaw | 60Analysis of the role of developmental regulatory factors during mouse embryogenesis | 8
| Jonathan Epstein | 5eTranscriptional regulation of cardiac development and function using mouse models | 8
| Robert Heuckeroth | 7dOur research is focused on the molecular and cellular mechanisms that control enteric nervous system development | 8
| Peter Klein | 100Early vertebrate development and pattern formation, Wnt signaling, chromatin and epigenetic regulation of early development, hematopoietic stem cell biology, neuropharmacology of bipolar disorder, lithium and glycogen synthase kinase-3 (GSK-3) | 8
| Andrew Modzelewski | 61Investigating the role and regulation of retrotransposons in development and disease | 8
| Edward Morrisey | 99Lung development, cardiac development, vascular development, Wnt signaling, regulation of gene transcription, GATA factors, forkhead factors | 8
| Mary Mullins | 74BMP signal transduction; molecular mechanisms of cell specification and maternal control in vertebrates | 8
| John Murray | 7cDevelopmental regulatory networks, dynamics of embryonic gene expression, and single-cell methods in C. elegans | 8
| Michael Pack | 8fResearch interests: Research in my laboratory is geared towards studying medically relevant aspects of digestive organ development | 8
| Jonathan Raper | 41Developmental neurobiology, especially axon guidance | 8
| Patrick Seale | 84Stem Cells, Embryonic development, Adipocyte progenitors, Brown adipose tissue, White adipose tissue, PRDM16, PPARgamma | 8
| Nancy Speck | 45Hematopoietic stem cells and leukemia using mouse models | 8
| Meera Sundaram | 46Tubulogenesis and Epithelial matrix biology in C. elegans | 8
| Wei Tong | 96Stem cell biology and regenerative medicine, leukemia, signal transduction and gene regulation, ribosome biogenesis, DNA replication | 8
| Julia Warren | 8
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Hematopoietic stem cell biology, granulopoiesis, genetics of bone marrow failure syndromes especially severe congenital neutropenia, mitochondria function and proteostasis in hematopoiesis, leukemia 9 |
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| Faculty | 33Brief Research Description | 8
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| Greg Bashaw | 4bAxon guidance, developmental neuroscience, Slit, Robo, Netrin. | 8
| Steve DiNardo | 36Migration and polarization of niche cells | 8
| Michael Granato | 54Axonal guidance, nerve regeneration and learning behaviors in zebrafish | 8
| Robert Heuckeroth | 7dOur research is focused on the molecular and cellular mechanisms that control enteric nervous system development | 8
| Olena Jacenko | 59Molecular mechanisms of skeletal development and blood cell differentiation. | 8
| Mary Mullins | 75BMP signal transduction; molecular mechanisms of cell specification and maternal control in vertebrates. | 8
| John Murray | 7cDevelopmental regulatory networks, dynamics of embryonic gene expression, and single-cell methods in C. elegans | 8
| Michael Pack | 5bZebrafish and mouse genetics, developmental biology, cancer, chemical genetics | 8
| Richard Poethig | 56miRNA, siRNA, RNAi, developmental genetics, developmental timing, plants. | 8
| Jonathan Raper | aeaxon guidance, developmental neurobiology, Molecular biology; tissue culture; Protein biochemistry; Videomicroscopy, expression cloning; mouse, chick, zebrafish. | 8
| Arndt Siekmann | 8
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Development of the vascular system with a focus on investigating the mechanisms leading to arterial-venous malformations 9 |
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| Meera Sundaram | 46Tubulogenesis and Epithelial matrix biology in C. elegans | 8
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| Stewart A Anderson | 7aGABAergic interneurons of the cerebral cortex in development and in disease (epilepsy, schizophrenia, autism) | 8
| Greg Bashaw | 63- Molecular mechanisms of axon growth and guidance during nervous system development. 8a - How axon guidance receptors specify attractive and repulsive signals and transmit these signals to the navigating growth cone. 36 - Formation of Neural Circuits at the Midline |
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| Elizabeth Bhoj | baOur lab works in translational genetics to improve diagnosis and treatment through the discovery, mechanistic understanding, and targeted treatment of novel human syndromes. | 8
| Michael Granato | 54Axonal guidance, nerve regeneration and learning behaviors in zebrafish | 8
| Judith Grinspan | aeOur lab studies the controls of the development of oligodendrocytes, the myelinating cells of the central nervous system, from stem cells through to myelination. | 8
| Robert Heuckeroth | 7eOur research is focused on the molecular and cellular mechanisms that control enteric nervous system development. | 8
| Peter Klein | 101Early vertebrate development and pattern formation, Wnt signaling, chromatin and epigenetic regulation of early development, hematopoietic stem cell biology, neuropharmacology of bipolar disorder, lithium and glycogen synthase kinase-3 (GSK-3). | 8
| Guo-Li Ming | cdOur research focuses on understanding brain development and developmental brain disorders using human genetics and patient-derived pluripotent stem cells (iPSCs)-based 2D and 3D organoid modes | 8
| Arghya Mukherjee | 84Emergent properties of the frontal cortex and associated circuits across normal development and mental disorders. | 8
| Xilma Ortiz-Gonzalez | 8
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My laboratory studies mechanism underlying neurodegeneration using ultra-rare pediatric monogenic disorders as disease models 9 |
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| Bushra Raj | 44Gene regulatory code and dynamics of neural development | 8
| Jonathan Raper | 41developmental neurobiology, especially axon guidance | 8
| Wenqin Luo | 64Development and Function of Mammalian Mechanosensory Dorsal Root Ganglion (DRG) Neurons | 8
| Katherine Uyhazi | 6eVisual system disorders, photoreceptor development, cell-based therapies for retinal regeneration | 8
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| Faculty | 33Brief Research Description | 8
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| Elizabeth Bhoj | baOur lab works in translational genetics to improve diagnosis and treatment through the discovery, mechanistic understanding, and targeted treatment of novel human syndromes. | 8
| Maya Capelson | 3fNuclear structure and its role in gene regulation 2c Spatial organization of the genome 34 Epigenetic memory of gene expression states |
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| Stephen DiNardo | 41We study how organs place and organize their niches. | 8
| Robert Heuckeroth | 7eOur research is focused on the molecular and cellular mechanisms that control enteric nervous system development. | 8
| Olena Jacenko | 59molecular mechanisms of skeletal development and blood cell differentiation. | 8
| Rajan Jain | 84Nuclear architecture, nuclear lamina, chromatin, epigenetics, genome organization, heart development, stem cell biology | 8
| Fanxin Long | 48We study the formation and maintenance of skeletal tissues. | 8
| Foteini Mourkioti | cfMuscle disorders, NF-kB signaling, M2 macrophages, muscle regeneration, stem cells, muscular dystrophy, telomeres, cardiomyopathy, mitochondria, oxidative stress, muscle atrophy, muscle wasting. | 8
| Mary Mullins | 75BMP signal transduction; molecular mechanisms of cell specification and maternal control in vertebrates. | 8
| Michael Pack | 7cResearch in my laboratory is geared towards studying medically relevant aspects of digestive organ development. | 8
| Michael Parmacek | 4eTranscriptional programs that regulate cardiovascular development | 8
| R. Scott Poethig | 4eGenetic regulation of the juvenile-to-adult transition in plants 35 The developmental function of RNAi in plants |
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| Ling Qin | 7aBone metabolism, stem cell biology, growth plate development, cancer bone metastasis, and signal transduction | 8
| Bushra Raj | 44Gene regulatory code and dynamics of neural development | 8
| Jonathan Raper | 41developmental neurobiology, especially axon guidance | 8
| Panteleimon Rompolas | 6aMechanisms of epithelial stem cell fate and plasticity in skin morphogenesis and regeneration | 8
| Nancy Speck | 45Hematopoietic stem cells and leukemia using mouse models | 8
| Patrick Seale | 138Obesity is the predominant risk factor for an expanding array of diseases including: type 2 diabetes, heart disease, stroke and cancer. Our lab investigates the transcriptional pathways that control the development, differentiation and function of adipose cells in normal development and in obesity. | 8
| Meera Sundaram | 46Tubulogenesis and Epithelial matrix biology in C. elegans | 8
| Wei Tong | 96Stem cell biology and regenerative medicine, leukemia, signal transduction and gene regulation, ribosome biogenesis, DNA replication | 8
| Julia Warren | 8
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Hematopoietic stem cell biology, granulopoiesis, genetics of bone marrow failure syndromes especially severe congenital neutropenia, mitochondria function and proteostasis in hematopoiesis, leukemia 9 |
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| Faculty | 33Brief Research Description | 8
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| George Cotsarelis | 44Stem cells; Hair follicle; Wounding; Aging; Skin cancer | 8
| Stephen DiNardo | 42Live-imaging to study stem cell behavior in real-time | 8
| Paul Gadue | c1My laboratory studies cell fate decisions, focusing on endoderm and mesoderm specification using mouse and human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells. | 8
| Judith Grinspan | aeOur lab studies the controls of the development of oligodendrocytes, the myelinating cells of the central nervous system, from stem cells through to myelination. | 8
| Robert Heuckeroth | 7eOur research is focused on the molecular and cellular mechanisms that control enteric nervous system development. | 8
| Olena Jacenko | 59molecular mechanisms of skeletal development and blood cell differentiation. | 8
| Rajan Jain | 84Nuclear architecture, nuclear lamina, chromatin, epigenetics, genome organization, heart development, stem cell biology | 8
| Peter Klein | 101Early vertebrate development and pattern formation, Wnt signaling, chromatin and epigenetic regulation of early development, hematopoietic stem cell biology, neuropharmacology of bipolar disorder, lithium and glycogen synthase kinase-3 (GSK-3). | 8
| Kang Ko | 8
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Epithelial-immune and mesenchymal-immune interactions in periodontitis (oral inflammatory disease) and wound healing process 9 |
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| Peter Kurre | 8
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The Kurre Lab is interested in the bidirectional crosstalk between hematopoietic stem and progenitor cells and components of the healthy bone marrow niche as well as leukemic blasts of the leukemic niche. Emphasis for our work is on the specific role of nanoscale sized extracellular vesicles. 9 |
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| Christopher Lengner | 100The overarching goal of my research program is to gain an understanding of the molecular mechanisms that govern stem cell potency and how dysregulation of these mechanisms can contribute to disease onset and progression, including oncogenesis. | 8
| Fanxin Long | 9dWe study mesenchymal stem/progenitor cells and their interactions with other cell ipopulations n either the bone marrow or the periosteal niche. | 8
| Guo-Li Ming | cdOur research focuses on understanding brain development and developmental brain disorders using human genetics and patient-derived pluripotent stem cells (iPSCs)-based 2D and 3D organoid modes | 8
| Edward Morrisey | 99Lung development, cardiac development, vascular development, Wnt signaling, regulation of gene transcription, GATA factors, forkhead factors | 8
| Foteini Mourkioti | cfmuscle disorders, NF-kB signaling, M2 macrophages, muscle regeneration, stem cells, muscular dystrophy, telomeres, cardiomyopathy, mitochondria, oxidative stress, muscle atrophy, muscle wasting. | 8
| Xilma Ortiz-Gonzalez | 8
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My laboratory studies mechanism underlying neurodegeneration using ultra-rare pediatric monogenic disorders as disease models 9 |
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| Panteleimon Rompolas | 6aMechanisms of epithelial stem cell fate and plasticity in skin morphogenesis and regeneration | 8
| Nancy Speck | 45Hematopoietic stem cells and leukemia using mouse models | 8
| Ling Qin | 7aBone metabolism, stem cell biology, growth plate development, cancer bone metastasis, and signal transduction | 8
| Wei Tong | 8
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Stem cell biology and regenerative medicine, leukemia, signal transduction and gene regulation, ribosome biogenesis, DNA replication 9 |
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| Julia Warren | 8
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Hematopoietic stem cell biology, granulopoiesis, genetics of bone marrow failure syndromes especially severe congenital neutropenia, mitochondria function and proteostasis in hematopoiesis, leukemia 9 |
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| Faculty | 33Brief Research Description | 8
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| George Cotsarelis | 44Stem cells; Hair follicle; Wounding; Aging; Skin cancer | 8
| Jonathan Epstein | 5eTranscriptional regulation of cardiac development and function using mouse models | 8
| Michael Granato | 54Axonal guidance, nerve regeneration and learning behaviors in zebrafish | 8
| Robert Heuckeroth | 7dEnteric nervous system precursor differentiation, migration, proliferation, axon guidance, and stem cell biology | 8
| Rajan Jain | 84Nuclear architecture, nuclear lamina, chromatin, epigenetics, genome organization, heart development, stem cell biology | 8
| Kang Ko | cbInvestigating the mechanisms by which fibroblasts from the oral cavity and skin differ at the functional and molecular level that can explain superior wound healing in the gingiva/gum tissue | 8
| Christopher Lengner | 100The overarching goal of my research program is to gain an understanding of the molecular mechanisms that govern stem cell potency and how dysregulation of these mechanisms can contribute to disease onset and progression, including oncogenesis. | 8
| Thomas Leung | 8fWe seek to improve our understanding of mammalian tissue regeneration and to develop novel therapeutics for regenerative medicine. | 8
| Fanxin Long | 8
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We study the biology of both bone remodeling, a continuous regenerative process necessary for maintaining bone integrity, and also bone regeneration during fracture repair. 9 |
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| Guo-Li Ming | cdOur research focuses on understanding brain development and developmental brain disorders using human genetics and patient-derived pluripotent stem cells (iPSCs)-based 2D and 3D organoid modes | 8
| Andrew Modzelewski | 61Investigating the role and regulation of retrotransposons in development and disease | 8
| Edward Morrisey | 99Lung development, cardiac development, vascular development, Wnt signaling, regulation of gene transcription, GATA factors, forkhead factors | 8
| Foteini Mourkioti | cfMuscle disorders, NF-kB signaling, M2 macrophages, muscle regeneration, stem cells, muscular dystrophy, telomeres, cardiomyopathy, mitochondria, oxidative stress, muscle atrophy, muscle wasting. | 8
| Panteleimon Rompolas | 6bMechanisms of epithelial stem cell fate and plasticity in skin morphogenesis and regeneration. | 8
| Yuanquan Song | 80Neural degeneration, Neural regeneration, Neurodegenerative diesases, Drosophila, Spinal cord injury, Tumorigenesis | 8
| Wei Tong | 96Stem cell biology and regenerative medicine, leukemia, signal transduction and gene regulation, ribosome biogenesis, DNA replication | 8
| Katherine Uyhazi | 6eVisual system disorders, photoreceptor development, cell-based therapies for retinal regeneration | 8
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| Montserrat Anguera | 8
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Epigenetic mechanisms of X-Chromosome Inactivation in immune cells & immune-related diseases 9 |
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| Marisa Bartolomei | 71The research in my laboratory focuses on the study of genomic imprinting and X inactivation in mice. | 8
| Elizabeth Bhoj | baOur lab works in translational genetics to improve diagnosis and treatment through the discovery, mechanistic understanding, and targeted treatment of novel human syndromes. | 8
| Colin Conine | 54The functions of small RNAs in fertility, inheritance, and development. | 8
| E. Bryan Crenshaw | 61Analysis of the role of developmental regulatory factors during mouse embryogenesis. | 8
| Jonathan Epstein | 5eTranscriptional regulation of cardiac development and function using mouse models | 8
| Paul Gadue | c1My laboratory studies cell fate decisions, focusing on endoderm and mesoderm specification using mouse and human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells. | 8
| Rajan Jain | 84Nuclear architecture, nuclear lamina, chromatin, epigenetics, genome organization, heart development, stem cell biology | 8
| Peter Klein | 125Early vertebrate development and pattern formation, Wnt signaling, chromatin and epigenetic regulation of early development, hematopoietic stem cell biology, neural stem cells and neurogenesis, neuropharmacology of bipolar disorder, lithium and glycogen synthase kinase-3 (GSK-3). | 8
| Christopher Lengner | 100The overarching goal of my research program is to gain an understanding of the molecular mechanisms that govern stem cell potency and how dysregulation of these mechanisms can contribute to disease onset and progression, including oncogenesis. | 8
| Fanxin Long | 61We study the metabolomic and epigenetic regulation of skeletal cell differentiation. | 8
| Andrew Modzelewski | 61Investigating the role and regulation of retrotransposons in development and disease | 8
| Edward Morrisey | 99lung development, cardiac development, vascular development, Wnt signaling, regulation of gene transcription, GATA factors, forkhead factors | 8
| Arghya Mukherjee | 84Emergent properties of the frontal cortex and associated circuits across normal development and mental disorders. | 8
| John Murray | 7cDevelopmental regulatory networks, dynamics of embryonic gene expression, and single-cell methods in C. elegans | 8
| Michael Parmacek | 4eTranscriptional programs that regulate cardiovascular development | 8
| Ling Qin | 7aBone metabolism, stem cell biology, growth plate development, cancer bone metastasis, and signal transduction | 8
| Panteleimon Rompolas | 6bMechanisms of epithelial stem cell fate and plasticity in skin morphogenesis and regeneration. | 8
| Patrick Seale | b0Our lab investigates the transcriptional pathways that control the development, differentiation and function of adipose cells in normal development and in obesity. | 8
| Nancy Speck | 45Hematopoietic stem cells and leukemia using mouse models | 8
| Wei Tong | 96Stem cell biology and regenerative medicine, leukemia, signal transduction and gene regulation, ribosome biogenesis, DNA replication | 8
| Jeremy Wang | d5Regulation of meiosis, silencing of transposable elements, piRNA biogenesis, DNA recombination, chromosome segregation, DNA double-strand break repair, chromosome synapsis, male infertility in humans. | 8
| Julia Warren | 8
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Hematopoietic stem cell biology, granulopoiesis, genetics of bone marrow failure syndromes especially severe congenital neutropenia, mitochondria function and proteostasis in hematopoiesis, leukemia 9 |
8
For information on how to apply for CAMB Faculty membership, please see the CAMB Bylaws.
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